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Pan-European Sarcoma Trials: Moving Forward in a Climate of Increasing Economic and Regulatory Pressure

Advances in sarcoma treatment are largely based on investigator-initiated, multicentric and interdisciplinary clinical trials. The EU's Good Clinical Practice Directive 2001/20/EC, effective since 2004, was meant to harmonize the conditions for clinical trials across Europe, but, instead, the c...

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Detalles Bibliográficos
Autores principales: Carrle, Dorothe, Dantonello, Tobias, Bielack, Stefan S.
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1906872/
http://dx.doi.org/10.1155/2007/76405
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author Carrle, Dorothe
Dantonello, Tobias
Bielack, Stefan S.
author_facet Carrle, Dorothe
Dantonello, Tobias
Bielack, Stefan S.
author_sort Carrle, Dorothe
collection PubMed
description Advances in sarcoma treatment are largely based on investigator-initiated, multicentric and interdisciplinary clinical trials. The EU's Good Clinical Practice Directive 2001/20/EC, effective since 2004, was meant to harmonize the conditions for clinical trials across Europe, but, instead, the challenge of initiating and running multinational, noncommercial clinical trials has become greater than ever. Institutions participating in existing noncommercial Pan-European studies are struggling to cope with increased administrative and financial burdens, and few new studies are initiated any more. The aim of a conference entitled “Pan-European Sarcoma Trials: Moving Forward in a Climate of Increasing Economic and Regulatory Pressure,” held in Stuttgart, Germany, 30 November–2 December 2006 as part of the European Science Foundation's ECT-program, was not only to provide an overview of currently active and planned multinational studies on osteo-, Ewing's, and soft tissue sarcoma, but also to draw on areas of synergy between various established sarcoma groups in Europe to define plausible survival strategies for collaborative, interdisciplinary, patient-oriented research.
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spelling pubmed-19068722007-07-19 Pan-European Sarcoma Trials: Moving Forward in a Climate of Increasing Economic and Regulatory Pressure Carrle, Dorothe Dantonello, Tobias Bielack, Stefan S. Sarcoma Meeting Report Advances in sarcoma treatment are largely based on investigator-initiated, multicentric and interdisciplinary clinical trials. The EU's Good Clinical Practice Directive 2001/20/EC, effective since 2004, was meant to harmonize the conditions for clinical trials across Europe, but, instead, the challenge of initiating and running multinational, noncommercial clinical trials has become greater than ever. Institutions participating in existing noncommercial Pan-European studies are struggling to cope with increased administrative and financial burdens, and few new studies are initiated any more. The aim of a conference entitled “Pan-European Sarcoma Trials: Moving Forward in a Climate of Increasing Economic and Regulatory Pressure,” held in Stuttgart, Germany, 30 November–2 December 2006 as part of the European Science Foundation's ECT-program, was not only to provide an overview of currently active and planned multinational studies on osteo-, Ewing's, and soft tissue sarcoma, but also to draw on areas of synergy between various established sarcoma groups in Europe to define plausible survival strategies for collaborative, interdisciplinary, patient-oriented research. Hindawi Publishing Corporation 2007 2007-06-17 /pmc/articles/PMC1906872/ http://dx.doi.org/10.1155/2007/76405 Text en Copyright © 2007 Dorothe Carrle et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Meeting Report
Carrle, Dorothe
Dantonello, Tobias
Bielack, Stefan S.
Pan-European Sarcoma Trials: Moving Forward in a Climate of Increasing Economic and Regulatory Pressure
title Pan-European Sarcoma Trials: Moving Forward in a Climate of Increasing Economic and Regulatory Pressure
title_full Pan-European Sarcoma Trials: Moving Forward in a Climate of Increasing Economic and Regulatory Pressure
title_fullStr Pan-European Sarcoma Trials: Moving Forward in a Climate of Increasing Economic and Regulatory Pressure
title_full_unstemmed Pan-European Sarcoma Trials: Moving Forward in a Climate of Increasing Economic and Regulatory Pressure
title_short Pan-European Sarcoma Trials: Moving Forward in a Climate of Increasing Economic and Regulatory Pressure
title_sort pan-european sarcoma trials: moving forward in a climate of increasing economic and regulatory pressure
topic Meeting Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1906872/
http://dx.doi.org/10.1155/2007/76405
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