Cargando…

Nuclear Factor 90(NF90) targeted to TAR RNA inhibits transcriptional activation of HIV-1

BACKGROUND: Examination of host cell-based inhibitors of HIV-1 transcription may be important for attenuating viral replication. We describe properties of a cellular double-stranded RNA binding protein with intrinsic affinity for HIV-1 TAR RNA that interferes with Tat/TAR interaction and inhibits vi...

Descripción completa

Detalles Bibliográficos
Autores principales: Agbottah, Emmanuel T, Traviss, Christine, McArdle, James, Karki, Sambhav, St Laurent, Georges C, Kumar, Ajit
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1910605/
https://www.ncbi.nlm.nih.gov/pubmed/17565699
http://dx.doi.org/10.1186/1742-4690-4-41

Ejemplares similares