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Intergenic Transcription, Cell-Cycle and the Developmentally Regulated Epigenetic Profile of the Human Beta-Globin Locus

Several lines of evidence have established strong links between transcriptional activity and specific post-translation modifications of histones. Here we show using RNA FISH that in erythroid cells, intergenic transcription in the human β-globin locus occurs over a region of greater than 250 kb incl...

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Detalles Bibliográficos
Autores principales:	Miles, Joanne, Mitchell, Jennifer A., Chakalova, Lyubomira, Goyenechea, Beatriz, Osborne, Cameron S., O'Neill, Laura, Tanimoto, Keiji, Engel, James Douglas, Fraser, Peter
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2007
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1910613/ https://www.ncbi.nlm.nih.gov/pubmed/17637845 http://dx.doi.org/10.1371/journal.pone.0000630

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