Fluorescent CXCR4 chemokine receptor antagonists: metal activated binding

The copper(ii) complex of a novel rhodamine-azamacrocycle conjugate binds to the CXCR4 chemokine receptor and competes effectively against anti-CXCR4 monoclonal antibodies. The copper macrocycle unit adopts a trans-II configuration in the solid state.

Detalles Bibliográficos
Autores principales: Khan, Abid, Silversides, Jon D., Madden, Leigh, Greenman, John, Archibald, Stephen J.
Formato: Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2007
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1913474/
https://www.ncbi.nlm.nih.gov/pubmed/17220989
http://dx.doi.org/10.1039/b614557d
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author Khan, Abid
Silversides, Jon D.
Madden, Leigh
Greenman, John
Archibald, Stephen J.
author_facet Khan, Abid
Silversides, Jon D.
Madden, Leigh
Greenman, John
Archibald, Stephen J.
author_sort Khan, Abid
collection PubMed
description The copper(ii) complex of a novel rhodamine-azamacrocycle conjugate binds to the CXCR4 chemokine receptor and competes effectively against anti-CXCR4 monoclonal antibodies. The copper macrocycle unit adopts a trans-II configuration in the solid state.
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spelling pubmed-19134742007-07-09 Fluorescent CXCR4 chemokine receptor antagonists: metal activated binding Khan, Abid Silversides, Jon D. Madden, Leigh Greenman, John Archibald, Stephen J. Chem Commun (Camb) Chemistry The copper(ii) complex of a novel rhodamine-azamacrocycle conjugate binds to the CXCR4 chemokine receptor and competes effectively against anti-CXCR4 monoclonal antibodies. The copper macrocycle unit adopts a trans-II configuration in the solid state. Royal Society of Chemistry 2007-01-28 2006-12-04 /pmc/articles/PMC1913474/ /pubmed/17220989 http://dx.doi.org/10.1039/b614557d Text en This journal is © The Royal Society of Chemistry 2006 http://creativecommons.org/licenses/by-nc/2.0/uk/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/2.0/uk/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Chemistry
Khan, Abid
Silversides, Jon D.
Madden, Leigh
Greenman, John
Archibald, Stephen J.
Fluorescent CXCR4 chemokine receptor antagonists: metal activated binding
title Fluorescent CXCR4 chemokine receptor antagonists: metal activated binding
title_full Fluorescent CXCR4 chemokine receptor antagonists: metal activated binding
title_fullStr Fluorescent CXCR4 chemokine receptor antagonists: metal activated binding
title_full_unstemmed Fluorescent CXCR4 chemokine receptor antagonists: metal activated binding
title_short Fluorescent CXCR4 chemokine receptor antagonists: metal activated binding
title_sort fluorescent cxcr4 chemokine receptor antagonists: metal activated binding
topic Chemistry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1913474/
https://www.ncbi.nlm.nih.gov/pubmed/17220989
http://dx.doi.org/10.1039/b614557d
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AT silversidesjond fluorescentcxcr4chemokinereceptorantagonistsmetalactivatedbinding
AT maddenleigh fluorescentcxcr4chemokinereceptorantagonistsmetalactivatedbinding
AT greenmanjohn fluorescentcxcr4chemokinereceptorantagonistsmetalactivatedbinding
AT archibaldstephenj fluorescentcxcr4chemokinereceptorantagonistsmetalactivatedbinding

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