Fluorescent CXCR4 chemokine receptor antagonists: metal activated binding

The copper(ii) complex of a novel rhodamine-azamacrocycle conjugate binds to the CXCR4 chemokine receptor and competes effectively against anti-CXCR4 monoclonal antibodies. The copper macrocycle unit adopts a trans-II configuration in the solid state.

Detalles Bibliográficos
Autores principales: Khan, Abid, Silversides, Jon D., Madden, Leigh, Greenman, John, Archibald, Stephen J.
Formato: Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2007
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1913474/
https://www.ncbi.nlm.nih.gov/pubmed/17220989
http://dx.doi.org/10.1039/b614557d

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1913474/
https://www.ncbi.nlm.nih.gov/pubmed/17220989
http://dx.doi.org/10.1039/b614557d

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