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Mouse oocytes fertilised by ICSI during in vitro maturation retain the ability to be activated after refertilisation in metaphase II and can generate Ca(2+ )oscillations
BACKGROUND: At fertilisation, mammalian oocytes are activated by oscillations of intracellular Ca(2+ )([Ca(2+)](i)). Phospholipase Cζ, which is introduced by fertilising spermatozoon, triggers [Ca(2+)](i )oscillations through the generation of inositol 1,4,5-triphosphate (IP(3)), which causes Ca(2+...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2007
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1913504/ https://www.ncbi.nlm.nih.gov/pubmed/17584490 http://dx.doi.org/10.1186/1471-213X-7-72 |