Genome-wide changes accompanying knockdown of fatty acid synthase in breast cancer

BACKGROUND: The lipogenic enzyme fatty acid synthase (FAS) is up-regulated in a wide variety of cancers, and is considered a potential metabolic oncogene by virtue of its ability to enhance tumor cell survival. Inhibition of tumor FAS causes both cell cycle arrest and apoptosis, indicating FAS is a...

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Detalles Bibliográficos
Autores principales: Knowles, Lynn M, Smith, Jeffrey W
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1913522/
https://www.ncbi.nlm.nih.gov/pubmed/17565694
http://dx.doi.org/10.1186/1471-2164-8-168

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