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Acquisition of Apoptotic Resistance in Cadmium-Transformed Human Prostate Epithelial Cells: Bcl-2 Overexpression Blocks the Activation of JNK Signal Transduction Pathway

BACKGROUND: We have recently shown that cadmium can induce malignant transformation of the human prostate epithelial cell line (RWPE-1) and that these cadmium-transformed prostate epithelial (CTPE) cells acquire apoptotic resistance concurrently with malignant phenotype. OBJECTIVE: The present study...

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Detalles Bibliográficos
Autores principales:	Qu, Wei, Ke, Hengning, Pi, Jingbo, Broderick, Daniel, French, John E., Webber, Mukta M., Waalkes, Michael P.
Formato:	Texto
Lenguaje:	English
Publicado:	National Institute of Environmental Health Sciences 2007
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1913575/ https://www.ncbi.nlm.nih.gov/pubmed/17637928 http://dx.doi.org/10.1289/ehp.10075

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