Selective redox regulation of cytokine receptor signaling by extracellular thioredoxin-1

The thiol-disulfide oxidoreductase thioredoxin-1 (Trx1) is known to be secreted by leukocytes and to exhibit cytokine-like properties. Extracellular effects of Trx1 require a functional active site, suggesting a redox-based mechanism of action. However, specific cell surface proteins and pathways co...

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Detalles Bibliográficos
Autores principales: Schwertassek, Ulla, Balmer, Yves, Gutscher, Marcus, Weingarten, Lars, Preuss, Marc, Engelhard, Johanna, Winkler, Monique, Dick, Tobias P
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2007
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1914094/
https://www.ncbi.nlm.nih.gov/pubmed/17557078
http://dx.doi.org/10.1038/sj.emboj.7601746

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1914094/
https://www.ncbi.nlm.nih.gov/pubmed/17557078
http://dx.doi.org/10.1038/sj.emboj.7601746

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