Perturbation of hyaluronan metabolism predisposes patients with type 1 diabetes mellitus to atherosclerosis

AIMS/HYPOTHESIS: Cardiovascular disease contributes to mortality in type 1 diabetes mellitus, but the specific pathophysiological mechanisms remain to be established. We recently showed that the endothelial glycocalyx, a protective layer of proteoglycans covering the endothelium, is severely perturb...

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Detalles Bibliográficos
Autores principales: Nieuwdorp, M., Holleman, F., de Groot, E., Vink, H., Gort, J., Kontush, A., Chapman, M. J., Hutten, B. A., Brouwer, C. B., Hoekstra, J. B. L., Kastelein, J. J. P., Stroes, E. S. G.
Formato: Texto
Lenguaje:English
Publicado: Springer-Verlag 2007
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1914278/
https://www.ncbi.nlm.nih.gov/pubmed/17415544
http://dx.doi.org/10.1007/s00125-007-0666-4

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