Rb-Mediated Neuronal Differentiation through Cell-Cycle–Independent Regulation of E2f3a

It has long been known that loss of the retinoblastoma protein (Rb) perturbs neural differentiation, but the underlying mechanism has never been solved. Rb absence impairs cell cycle exit and triggers death of some neurons, so differentiation defects may well be indirect. Indeed, we show that abnorm...

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Detalles Bibliográficos
Autores principales: Chen, Danian, Opavsky, Rene, Pacal, Marek, Tanimoto, Naoyuki, Wenzel, Pamela, Seeliger, Mathias W, Leone, Gustavo, Bremner, Rod
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2007
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1914394/
https://www.ncbi.nlm.nih.gov/pubmed/17608565
http://dx.doi.org/10.1371/journal.pbio.0050179

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1914394/
https://www.ncbi.nlm.nih.gov/pubmed/17608565
http://dx.doi.org/10.1371/journal.pbio.0050179

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