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Rb-Mediated Neuronal Differentiation through Cell-Cycle–Independent Regulation of E2f3a
It has long been known that loss of the retinoblastoma protein (Rb) perturbs neural differentiation, but the underlying mechanism has never been solved. Rb absence impairs cell cycle exit and triggers death of some neurons, so differentiation defects may well be indirect. Indeed, we show that abnorm...
| Autores principales: | , , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2007
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1914394/ https://www.ncbi.nlm.nih.gov/pubmed/17608565 http://dx.doi.org/10.1371/journal.pbio.0050179 |