Mitochondrial Cell Death Control in Familial Parkinson Disease

Many sporadic cases of Parkinsons disease have mutations in the PINK protein kinase, whose substrate is now revealed to be a protein that protects mitochondria from oxidative stress.

Detalles Bibliográficos
Autores principales: Kroemer, Guido, Blomgren, Klas
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2007
Materias:
Primer
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1914412/
https://www.ncbi.nlm.nih.gov/pubmed/17638420
http://dx.doi.org/10.1371/journal.pbio.0050206
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author Kroemer, Guido
Blomgren, Klas
author_facet Kroemer, Guido
Blomgren, Klas
author_sort Kroemer, Guido
collection PubMed
description Many sporadic cases of Parkinsons disease have mutations in the PINK protein kinase, whose substrate is now revealed to be a protein that protects mitochondria from oxidative stress.
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spelling pubmed-19144122007-09-06 Mitochondrial Cell Death Control in Familial Parkinson Disease Kroemer, Guido Blomgren, Klas PLoS Biol Primer Many sporadic cases of Parkinsons disease have mutations in the PINK protein kinase, whose substrate is now revealed to be a protein that protects mitochondria from oxidative stress. Public Library of Science 2007-07 2007-07-17 /pmc/articles/PMC1914412/ /pubmed/17638420 http://dx.doi.org/10.1371/journal.pbio.0050206 Text en © 2007 Kroemer and Blomgren. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.
spellingShingle Primer
Kroemer, Guido
Blomgren, Klas
Mitochondrial Cell Death Control in Familial Parkinson Disease
title Mitochondrial Cell Death Control in Familial Parkinson Disease
title_full Mitochondrial Cell Death Control in Familial Parkinson Disease
title_fullStr Mitochondrial Cell Death Control in Familial Parkinson Disease
title_full_unstemmed Mitochondrial Cell Death Control in Familial Parkinson Disease
title_short Mitochondrial Cell Death Control in Familial Parkinson Disease
title_sort mitochondrial cell death control in familial parkinson disease
topic Primer
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1914412/
https://www.ncbi.nlm.nih.gov/pubmed/17638420
http://dx.doi.org/10.1371/journal.pbio.0050206
work_keys_str_mv AT kroemerguido mitochondrialcelldeathcontrolinfamilialparkinsondisease
AT blomgrenklas mitochondrialcelldeathcontrolinfamilialparkinsondisease

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