Cellular Uptake of Cationic Polymer-DNA Complexes Via Caveolae Plays a Pivotal Role in Gene Transfection in COS-7 Cells

PURPOSE: Knowledge about the uptake mechanism and subsequent intracellular routing of non-viral gene delivery systems is important for the development of more efficient carriers. In this study we compared two established cationic polymers pDMAEMA and PEI with regard to their transfection efficiency...

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Detalles Bibliográficos
Autores principales: van der Aa, M. A. E. M., Huth, U. S., Häfele, S. Y., Schubert, R., Oosting, R. S., Mastrobattista, E., Hennink, W. E., Peschka-Süss, R., Koning, G. A., Crommelin, D. J. A.
Formato: Texto
Lenguaje:English
Publicado: Kluwer Academic Publishers-Plenum Publishers 2007
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1915651/
https://www.ncbi.nlm.nih.gov/pubmed/17385010
http://dx.doi.org/10.1007/s11095-007-9287-3

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