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Attenuation-Corrected vs. Nonattenuation-Corrected 2-Deoxy-2-[F-18]fluoro-d-glucose-Positron Emission Tomography in Oncology, A Systematic Review
PURPOSE: To perform a systematic review and meta-analysis to determine the diagnostic accuracy of attenuation-corrected (AC) vs. nonattenuation-corrected (NAC) 2-deoxy-2-[F-18]fluoro-d-glucose-positron emission tomography (FDG-PET) in oncological patients. PROCEDURES: Following a comprehensive searc...
Autores principales: | , , , , , |
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Formato: | Texto |
Lenguaje: | English |
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Springer-Verlag
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1915656/ https://www.ncbi.nlm.nih.gov/pubmed/17318671 http://dx.doi.org/10.1007/s11307-007-0076-5 |
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author | Joshi, Urvi Raijmakers, Pieter G. H. M. Riphagen, Ingrid I. Teule, Gerrit J. J. van Lingen, Arthur Hoekstra, Otto S. |
author_facet | Joshi, Urvi Raijmakers, Pieter G. H. M. Riphagen, Ingrid I. Teule, Gerrit J. J. van Lingen, Arthur Hoekstra, Otto S. |
author_sort | Joshi, Urvi |
collection | PubMed |
description | PURPOSE: To perform a systematic review and meta-analysis to determine the diagnostic accuracy of attenuation-corrected (AC) vs. nonattenuation-corrected (NAC) 2-deoxy-2-[F-18]fluoro-d-glucose-positron emission tomography (FDG-PET) in oncological patients. PROCEDURES: Following a comprehensive search of the literature, two reviewers independently assessed the methodological quality of eligible studies. The diagnostic value of AC was studied through its sensitivity/specificity compared to histology, and by comparing the relative lesion detection rate reported with NAC-PET vs. AC, for full-ring and dual-head coincidence PET (FR- and DH-PET, respectively). RESULTS: Twelve studies were included. For FR-PET, the pooled sensitivity/specificity on a patient basis was 64/97% for AC and 62/99% for NAC, respectively. Pooled lesion detection with NAC vs. AC was 98% [95% confidence interval (95% CI): 96–99%, n = 1,012 lesions] for FR-PET, and 88% (95% CI:81–94%, n = 288 lesions) for DH-PET. CONCLUSIONS: Findings suggest similar sensitivity/specificity and lesion detection for NAC vs. AC FR-PET and significantly higher lesion detection for NAC vs. AC DH-PET. |
format | Text |
id | pubmed-1915656 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2007 |
publisher | Springer-Verlag |
record_format | MEDLINE/PubMed |
spelling | pubmed-19156562007-07-13 Attenuation-Corrected vs. Nonattenuation-Corrected 2-Deoxy-2-[F-18]fluoro-d-glucose-Positron Emission Tomography in Oncology, A Systematic Review Joshi, Urvi Raijmakers, Pieter G. H. M. Riphagen, Ingrid I. Teule, Gerrit J. J. van Lingen, Arthur Hoekstra, Otto S. Mol Imaging Biol Research Article PURPOSE: To perform a systematic review and meta-analysis to determine the diagnostic accuracy of attenuation-corrected (AC) vs. nonattenuation-corrected (NAC) 2-deoxy-2-[F-18]fluoro-d-glucose-positron emission tomography (FDG-PET) in oncological patients. PROCEDURES: Following a comprehensive search of the literature, two reviewers independently assessed the methodological quality of eligible studies. The diagnostic value of AC was studied through its sensitivity/specificity compared to histology, and by comparing the relative lesion detection rate reported with NAC-PET vs. AC, for full-ring and dual-head coincidence PET (FR- and DH-PET, respectively). RESULTS: Twelve studies were included. For FR-PET, the pooled sensitivity/specificity on a patient basis was 64/97% for AC and 62/99% for NAC, respectively. Pooled lesion detection with NAC vs. AC was 98% [95% confidence interval (95% CI): 96–99%, n = 1,012 lesions] for FR-PET, and 88% (95% CI:81–94%, n = 288 lesions) for DH-PET. CONCLUSIONS: Findings suggest similar sensitivity/specificity and lesion detection for NAC vs. AC FR-PET and significantly higher lesion detection for NAC vs. AC DH-PET. Springer-Verlag 2007-02-21 2007-05 /pmc/articles/PMC1915656/ /pubmed/17318671 http://dx.doi.org/10.1007/s11307-007-0076-5 Text en © Academy of Molecular Imaging 2007 |
spellingShingle | Research Article Joshi, Urvi Raijmakers, Pieter G. H. M. Riphagen, Ingrid I. Teule, Gerrit J. J. van Lingen, Arthur Hoekstra, Otto S. Attenuation-Corrected vs. Nonattenuation-Corrected 2-Deoxy-2-[F-18]fluoro-d-glucose-Positron Emission Tomography in Oncology, A Systematic Review |
title | Attenuation-Corrected vs. Nonattenuation-Corrected 2-Deoxy-2-[F-18]fluoro-d-glucose-Positron Emission Tomography in Oncology, A Systematic Review |
title_full | Attenuation-Corrected vs. Nonattenuation-Corrected 2-Deoxy-2-[F-18]fluoro-d-glucose-Positron Emission Tomography in Oncology, A Systematic Review |
title_fullStr | Attenuation-Corrected vs. Nonattenuation-Corrected 2-Deoxy-2-[F-18]fluoro-d-glucose-Positron Emission Tomography in Oncology, A Systematic Review |
title_full_unstemmed | Attenuation-Corrected vs. Nonattenuation-Corrected 2-Deoxy-2-[F-18]fluoro-d-glucose-Positron Emission Tomography in Oncology, A Systematic Review |
title_short | Attenuation-Corrected vs. Nonattenuation-Corrected 2-Deoxy-2-[F-18]fluoro-d-glucose-Positron Emission Tomography in Oncology, A Systematic Review |
title_sort | attenuation-corrected vs. nonattenuation-corrected 2-deoxy-2-[f-18]fluoro-d-glucose-positron emission tomography in oncology, a systematic review |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1915656/ https://www.ncbi.nlm.nih.gov/pubmed/17318671 http://dx.doi.org/10.1007/s11307-007-0076-5 |
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