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Cation induced differential effect on structural and functional properties of Mycobacterium tuberculosis α-Isopropylmalate synthase

BACKGROUND: α-isopropylmalate synthase (MtαIPMS), an enzyme that catalyzes the first committed step of the leucine biosynthetic pathway of Mycobacterium tuberculosis is a potential drug target for the anti-tuberculosis drugs. Cations induce differential effect of activation and inhibition of MtαIPMS...

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Detalles Bibliográficos
Autores principales:	Singh, Kulwant, Bhakuni, Vinod
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2007
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1919377/ https://www.ncbi.nlm.nih.gov/pubmed/17577419 http://dx.doi.org/10.1186/1472-6807-7-39

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