Cargando…

Novel Peptide Sequence (“IQ-tag”) with High Affinity for NIR Fluorochromes Allows Protein and Cell Specific Labeling for In Vivo Imaging

BACKGROUND: Probes that allow site-specific protein labeling have become critical tools for visualizing biological processes. METHODS: Here we used phage display to identify a novel peptide sequence with nanomolar affinity for near infrared (NIR) (benz)indolium fluorochromes. The developed peptide s...

Descripción completa

Detalles Bibliográficos
Autores principales: Kelly, Kimberly A., Carson, Jonathan, McCarthy, Jason R., Weissleder, Ralph
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1919420/
https://www.ncbi.nlm.nih.gov/pubmed/17653285
http://dx.doi.org/10.1371/journal.pone.0000665