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A statistical learning approach to the modeling of chromatographic retention of oligonucleotides incorporating sequence and secondary structure data

We propose a new model for predicting the retention time of oligonucleotides. The model is based on ν support vector regression using features derived from base sequence and predicted secondary structure of oligonucleotides. Because of the secondary structure information, the model is applicable eve...

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Detalles Bibliográficos
Autores principales: Sturm, Marc, Quinten, Sascha, Huber, Christian G., Kohlbacher, Oliver
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1919494/
https://www.ncbi.nlm.nih.gov/pubmed/17567619
http://dx.doi.org/10.1093/nar/gkm338