Cargando…
Enhanced oligonucleotide–nanoparticle conjugate stability using thioctic acid modified oligonucleotides
Metallic nanoparticles of gold functionalized with oligonucleotides conventionally use a terminal thiol modification and have been used in a wide range of applications. Although readily available, the oligonucleotide–nanoparticle conjugates prepared in this way suffer from a lack of stability when e...
Autores principales: | Dougan, Jennifer A., Karlsson, Camilla, Smith, W. Ewen, Graham, Duncan |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2007
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1920241/ https://www.ncbi.nlm.nih.gov/pubmed/17488844 http://dx.doi.org/10.1093/nar/gkm237 |
Ejemplares similares
-
Thioctic Acid Derivatives as Building Blocks to Incorporate DNA Oligonucleotides onto Gold Nanoparticles
por: Pérez-Rentero, Sónia, et al.
Publicado: (2014) -
Lipid–oligonucleotide conjugates for bioapplications
por: Li, Xiaowei, et al.
Publicado: (2020) -
Conjugation of oligonucleotides with activated carbamate reagents prepared by the Ugi reaction for oligonucleotide library synthesis
por: Kita, Ryosuke, et al.
Publicado: (2022) -
Fatty acid conjugation enhances potency of antisense oligonucleotides in muscle
por: Prakash, Thazha P, et al.
Publicado: (2019) -
Covalently attached intercalators restore duplex stability and splice-switching activity to triazole-modified oligonucleotides
por: Dysko, Anna, et al.
Publicado: (2022)