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Endonuclease-independent insertion provides an alternative pathway for L1 retrotransposition in the human genome
LINE-1 elements (L1s) are a family of highly successful retrotransposons comprising ∼17% of the human genome, the majority of which have inserted through an endonuclease-dependent mechanism termed target-primed reverse transcription. Recent in vitro analyses suggest that in the absence of non-homolo...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2007
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1920257/ https://www.ncbi.nlm.nih.gov/pubmed/17517773 http://dx.doi.org/10.1093/nar/gkm317 |