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Profiling the DNA-binding specificities of engineered Cys2His2 zinc finger domains using a rapid cell-based method
The C(2)H(2) zinc finger is the most commonly utilized framework for engineering DNA-binding domains with novel specificities. Many different selection strategies have been developed to identify individual fingers that possess a particular DNA-binding specificity from a randomized library. In these...
| Autores principales: | , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2007
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1920264/ https://www.ncbi.nlm.nih.gov/pubmed/17537811 http://dx.doi.org/10.1093/nar/gkm385 |