Treatment of multiple liver metastasis from gastric carcinoma

BACKGROUND: The efficacy of operative resection of liver metastasis from colorectal cancer has been established. However, a treatment for liver metastasis from gastric cancer has not yet been established. In this study, we evaluated the efficacy of hepatic arterial infusion for synchronous hepatic m...

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Detalles Bibliográficos
Autores principales: Ojima, Hitoshi, Ootake, Sayaka, Yokobori, Takehiko, Mochida, Yasushi, Hosouchi, Yasuo, Nishida, Yasuji, Kuwano, Hiroyuki
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1920512/
https://www.ncbi.nlm.nih.gov/pubmed/17584926
http://dx.doi.org/10.1186/1477-7819-5-70
Descripción
Sumario:BACKGROUND: The efficacy of operative resection of liver metastasis from colorectal cancer has been established. However, a treatment for liver metastasis from gastric cancer has not yet been established. In this study, we evaluated the efficacy of hepatic arterial infusion for synchronous hepatic metastasis from gastric cancer. PATIENTS AND METHODS: This study consisted of 37 patients [HAI group; 18 and non-HAI group; 19] with synchronous multiple liver metastases from gastric cancer at Gunma Prefecture Saiseikai-Maebashi Hospital. We retrospectively analyzed the efficacy of HAI. RESULTS: Response rate (CR + PR) of HAI was 83%. However, HAI treatment did not affect any improvement in the survival rate. CONCLUSION: HAI is an effective treatment for control of liver metastasis specifically. The factor effective for an improvement in the survival rate was possibly that of gastrectomy.

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