Treatment of multiple liver metastasis from gastric carcinoma

BACKGROUND: The efficacy of operative resection of liver metastasis from colorectal cancer has been established. However, a treatment for liver metastasis from gastric cancer has not yet been established. In this study, we evaluated the efficacy of hepatic arterial infusion for synchronous hepatic m...

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Autores principales: Ojima, Hitoshi, Ootake, Sayaka, Yokobori, Takehiko, Mochida, Yasushi, Hosouchi, Yasuo, Nishida, Yasuji, Kuwano, Hiroyuki
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1920512/
https://www.ncbi.nlm.nih.gov/pubmed/17584926
http://dx.doi.org/10.1186/1477-7819-5-70
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author Ojima, Hitoshi
Ootake, Sayaka
Yokobori, Takehiko
Mochida, Yasushi
Hosouchi, Yasuo
Nishida, Yasuji
Kuwano, Hiroyuki
author_facet Ojima, Hitoshi
Ootake, Sayaka
Yokobori, Takehiko
Mochida, Yasushi
Hosouchi, Yasuo
Nishida, Yasuji
Kuwano, Hiroyuki
author_sort Ojima, Hitoshi
collection PubMed
description BACKGROUND: The efficacy of operative resection of liver metastasis from colorectal cancer has been established. However, a treatment for liver metastasis from gastric cancer has not yet been established. In this study, we evaluated the efficacy of hepatic arterial infusion for synchronous hepatic metastasis from gastric cancer. PATIENTS AND METHODS: This study consisted of 37 patients [HAI group; 18 and non-HAI group; 19] with synchronous multiple liver metastases from gastric cancer at Gunma Prefecture Saiseikai-Maebashi Hospital. We retrospectively analyzed the efficacy of HAI. RESULTS: Response rate (CR + PR) of HAI was 83%. However, HAI treatment did not affect any improvement in the survival rate. CONCLUSION: HAI is an effective treatment for control of liver metastasis specifically. The factor effective for an improvement in the survival rate was possibly that of gastrectomy.
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spelling pubmed-19205122007-07-17 Treatment of multiple liver metastasis from gastric carcinoma Ojima, Hitoshi Ootake, Sayaka Yokobori, Takehiko Mochida, Yasushi Hosouchi, Yasuo Nishida, Yasuji Kuwano, Hiroyuki World J Surg Oncol Research BACKGROUND: The efficacy of operative resection of liver metastasis from colorectal cancer has been established. However, a treatment for liver metastasis from gastric cancer has not yet been established. In this study, we evaluated the efficacy of hepatic arterial infusion for synchronous hepatic metastasis from gastric cancer. PATIENTS AND METHODS: This study consisted of 37 patients [HAI group; 18 and non-HAI group; 19] with synchronous multiple liver metastases from gastric cancer at Gunma Prefecture Saiseikai-Maebashi Hospital. We retrospectively analyzed the efficacy of HAI. RESULTS: Response rate (CR + PR) of HAI was 83%. However, HAI treatment did not affect any improvement in the survival rate. CONCLUSION: HAI is an effective treatment for control of liver metastasis specifically. The factor effective for an improvement in the survival rate was possibly that of gastrectomy. BioMed Central 2007-06-21 /pmc/articles/PMC1920512/ /pubmed/17584926 http://dx.doi.org/10.1186/1477-7819-5-70 Text en Copyright © 2007 Ojima et al; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License ( (http://creativecommons.org/licenses/by/2.0) ), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research
Ojima, Hitoshi
Ootake, Sayaka
Yokobori, Takehiko
Mochida, Yasushi
Hosouchi, Yasuo
Nishida, Yasuji
Kuwano, Hiroyuki
Treatment of multiple liver metastasis from gastric carcinoma
title Treatment of multiple liver metastasis from gastric carcinoma
title_full Treatment of multiple liver metastasis from gastric carcinoma
title_fullStr Treatment of multiple liver metastasis from gastric carcinoma
title_full_unstemmed Treatment of multiple liver metastasis from gastric carcinoma
title_short Treatment of multiple liver metastasis from gastric carcinoma
title_sort treatment of multiple liver metastasis from gastric carcinoma
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1920512/
https://www.ncbi.nlm.nih.gov/pubmed/17584926
http://dx.doi.org/10.1186/1477-7819-5-70
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