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Tyrosine phosphatases such as SHP-2 act in a balance with Src-family kinases in stabilization of postsynaptic clusters of acetylcholine receptors

BACKGROUND: Development of neural networks requires that synapses are formed, eliminated and stabilized. At the neuromuscular junction (NMJ), agrin/MuSK signaling, by triggering downstream pathways, causes clustering and phosphorylation of postsynaptic acetylcholine receptors (AChRs). Postnatally, A...

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Detalles Bibliográficos
Autores principales:	Camilleri, Alain A, Willmann, Raffaella, Sadasivam, Gayathri, Lin, Shuo, Rüegg, Markus A, Gesemann, Matthias, Fuhrer, Christian
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2007
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1924855/ https://www.ncbi.nlm.nih.gov/pubmed/17605785 http://dx.doi.org/10.1186/1471-2202-8-46

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