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Applicability of DNA pools on 500 K SNP microarrays for cost-effective initial screens in genomewide association studies

BACKGROUND: Genetic influences underpinning complex traits are thought to involve multiple quantitative trait loci (QTLs) of small effect size. Detection of such QTL associations requires systematic screening of large numbers of DNA markers within large sample populations. Using pooled DNA on SNP mi...

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Detalles Bibliográficos
Autores principales:	Docherty, Sophia J, Butcher, Lee M, Schalkwyk, Leonard C, Plomin, Robert
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2007
Materias:	Methodology Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1925094/ https://www.ncbi.nlm.nih.gov/pubmed/17610740 http://dx.doi.org/10.1186/1471-2164-8-214

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