Population Bottlenecks as a Potential Major Shaping Force of Human Genome Architecture

The modern synthetic view of human evolution proposes that the fixation of novel mutations is driven by the balance among selective advantage, selective disadvantage, and genetic drift. When considering the global architecture of the human genome, the same model can be applied to understanding the r...

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Detalles Bibliográficos
Autores principales: Gherman, Adrian, Chen, Peter E, Teslovich, Tanya M, Stankiewicz, Pawel, Withers, Marjorie, Kashuk, Carl S, Chakravarti, Aravinda, Lupski, James R, Cutler, David J, Katsanis, Nicholas
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2007
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1925129/
https://www.ncbi.nlm.nih.gov/pubmed/17658953
http://dx.doi.org/10.1371/journal.pgen.0030119

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1925129/
https://www.ncbi.nlm.nih.gov/pubmed/17658953
http://dx.doi.org/10.1371/journal.pgen.0030119

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