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Validation of the SCID-hu Thy/Liv Mouse Model with Four Classes of Licensed Antiretrovirals
BACKGROUND: The SCID-hu Thy/Liv mouse model of HIV-1 infection is a useful platform for the preclinical evaluation of antiviral efficacy in vivo. We performed this study to validate the model with representatives of all four classes of licensed antiretrovirals. METHODOLOGY/PRINCIPAL FINDINGS: Endpoi...
Autores principales: | , , , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1925140/ https://www.ncbi.nlm.nih.gov/pubmed/17668043 http://dx.doi.org/10.1371/journal.pone.0000655 |