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Validation of the SCID-hu Thy/Liv Mouse Model with Four Classes of Licensed Antiretrovirals

BACKGROUND: The SCID-hu Thy/Liv mouse model of HIV-1 infection is a useful platform for the preclinical evaluation of antiviral efficacy in vivo. We performed this study to validate the model with representatives of all four classes of licensed antiretrovirals. METHODOLOGY/PRINCIPAL FINDINGS: Endpoi...

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Detalles Bibliográficos
Autores principales:	Stoddart, Cheryl A., Bales, Cheryl A., Bare, Jennifer C., Chkhenkeli, George, Galkina, Sofiya A., Kinkade, April N., Moreno, Mary E., Rivera, José M., Ronquillo, Rollie E., Sloan, Barbara, Black, Paul L.
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2007
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1925140/ https://www.ncbi.nlm.nih.gov/pubmed/17668043 http://dx.doi.org/10.1371/journal.pone.0000655

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