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Cooperation between Wnt and Notch signalling in human breast cancer

The Wnt and Notch signalling pathways play major roles in mammary gland development and tumourigenesis. During development, these pathways have opposing effects. However, in a recent paper Ayyanan and coworkers show that expression of Wnt1 is sufficient to transform primary human mammary epithelial...

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Detalles Bibliográficos
Autores principales: Collu, Giovanna M, Brennan, Keith
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1929088/
https://www.ncbi.nlm.nih.gov/pubmed/17531087
http://dx.doi.org/10.1186/bcr1671