An annotation infrastructure for the analysis and interpretation of Affymetrix exon array data

Affymetrix exon arrays contain probesets intended to target every known and predicted exon in the entire genome, posing significant challenges for high-throughput genome-wide data analysis. X:MAP , an annotation database, and exonmap , a BioConductor/R package, are designed to support fine-grained a...

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Detalles Bibliográficos
Autores principales: Okoniewski, Michał J, Yates, Tim, Dibben, Siân, Miller, Crispin J
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Software
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1929135/
https://www.ncbi.nlm.nih.gov/pubmed/17498294
http://dx.doi.org/10.1186/gb-2007-8-5-r79
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author Okoniewski, Michał J
Yates, Tim
Dibben, Siân
Miller, Crispin J
author_facet Okoniewski, Michał J
Yates, Tim
Dibben, Siân
Miller, Crispin J
author_sort Okoniewski, Michał J
collection PubMed
description Affymetrix exon arrays contain probesets intended to target every known and predicted exon in the entire genome, posing significant challenges for high-throughput genome-wide data analysis. X:MAP , an annotation database, and exonmap , a BioConductor/R package, are designed to support fine-grained analysis of exon array data. The system supports the application of standard statistical techniques, prior to the use of genome scale annotation to provide gene-, transcript- and exon-level summaries and visualization tools.
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spelling pubmed-19291352007-07-21 An annotation infrastructure for the analysis and interpretation of Affymetrix exon array data Okoniewski, Michał J Yates, Tim Dibben, Siân Miller, Crispin J Genome Biol Software Affymetrix exon arrays contain probesets intended to target every known and predicted exon in the entire genome, posing significant challenges for high-throughput genome-wide data analysis. X:MAP , an annotation database, and exonmap , a BioConductor/R package, are designed to support fine-grained analysis of exon array data. The system supports the application of standard statistical techniques, prior to the use of genome scale annotation to provide gene-, transcript- and exon-level summaries and visualization tools. BioMed Central 2007 2007-05-11 /pmc/articles/PMC1929135/ /pubmed/17498294 http://dx.doi.org/10.1186/gb-2007-8-5-r79 Text en Copyright © 2007 Okoniewski et al.; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an open access article distributed under the terms of the Creative Commons Attribution License ( (http://creativecommons.org/licenses/by/2.0) ), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Software
Okoniewski, Michał J
Yates, Tim
Dibben, Siân
Miller, Crispin J
An annotation infrastructure for the analysis and interpretation of Affymetrix exon array data
title An annotation infrastructure for the analysis and interpretation of Affymetrix exon array data
title_full An annotation infrastructure for the analysis and interpretation of Affymetrix exon array data
title_fullStr An annotation infrastructure for the analysis and interpretation of Affymetrix exon array data
title_full_unstemmed An annotation infrastructure for the analysis and interpretation of Affymetrix exon array data
title_short An annotation infrastructure for the analysis and interpretation of Affymetrix exon array data
title_sort annotation infrastructure for the analysis and interpretation of affymetrix exon array data
topic Software
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1929135/
https://www.ncbi.nlm.nih.gov/pubmed/17498294
http://dx.doi.org/10.1186/gb-2007-8-5-r79
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