Modular architecture of protein structures and allosteric communications: potential implications for signaling proteins and regulatory linkages

BACKGROUND: Allosteric communications are vital for cellular signaling. Here we explore a relationship between protein architectural organization and shortcuts in signaling pathways. RESULTS: We show that protein domains consist of modules interconnected by residues that mediate signaling through th...

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Detalles Bibliográficos
Autores principales: del Sol, Antonio, Araúzo-Bravo, Marcos J, Amoros, Dolors, Nussinov, Ruth
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1929157/
https://www.ncbi.nlm.nih.gov/pubmed/17531094
http://dx.doi.org/10.1186/gb-2007-8-5-r92

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