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Unequal evolutionary conservation of human protein interactions in interologous networks

BACKGROUND: Protein-protein interaction (PPI) networks have been transferred between organisms using interologs, allowing model organisms to supplement the interactomes of higher eukaryotes. However, the conservation of various network components has not been fully explored. Unequal conservation of...

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Detalles Bibliográficos
Autores principales: Brown, Kevin R, Jurisica, Igor
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1929159/
https://www.ncbi.nlm.nih.gov/pubmed/17535438
http://dx.doi.org/10.1186/gb-2007-8-5-r95