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Toxicology evaluation of radiotracer doses of 3'-deoxy-3'-[(18)F]fluorothymidine ((18)F-FLT) for human PET imaging: Laboratory analysis of serial blood samples and comparison to previously investigated therapeutic FLT doses

BACKGROUND: (18)F-FLT is a novel PET radiotracer which has demonstrated a strong potential utility for imaging cellular proliferation in human tumors in vivo. To facilitate future regulatory approval of (18)F-FLT for clinical use, we wished to demonstrate the safety of radiotracer doses of (18)F-FLT...

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Detalles Bibliográficos
Autores principales: Turcotte, Eric, Wiens, Linda W, Grierson, John R, Peterson, Lanell M, Wener, Mark H, Vesselle, Hubert
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1931583/
https://www.ncbi.nlm.nih.gov/pubmed/17608943
http://dx.doi.org/10.1186/1471-2385-7-3

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