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Selecton 2007: advanced models for detecting positive and purifying selection using a Bayesian inference approach

Biologically significant sites in a protein may be identified by contrasting the rates of synonymous (K(s)) and non-synonymous (K(a)) substitutions. This enables the inference of site-specific positive Darwinian selection and purifying selection. We present here Selecton version 2.2 (http://selecton...

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Detalles Bibliográficos
Autores principales: Stern, Adi, Doron-Faigenboim, Adi, Erez, Elana, Martz, Eric, Bacharach, Eran, Pupko, Tal
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1933148/
https://www.ncbi.nlm.nih.gov/pubmed/17586822
http://dx.doi.org/10.1093/nar/gkm382