Cargando…
Selecton 2007: advanced models for detecting positive and purifying selection using a Bayesian inference approach
Biologically significant sites in a protein may be identified by contrasting the rates of synonymous (K(s)) and non-synonymous (K(a)) substitutions. This enables the inference of site-specific positive Darwinian selection and purifying selection. We present here Selecton version 2.2 (http://selecton...
Autores principales: | Stern, Adi, Doron-Faigenboim, Adi, Erez, Elana, Martz, Eric, Bacharach, Eran, Pupko, Tal |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2007
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1933148/ https://www.ncbi.nlm.nih.gov/pubmed/17586822 http://dx.doi.org/10.1093/nar/gkm382 |
Ejemplares similares
-
Evolutionary Modeling of Rate Shifts Reveals Specificity Determinants in HIV-1 Subtypes
por: Penn, Osnat, et al.
Publicado: (2008) -
ConSurf 2010: calculating evolutionary conservation in sequence and structure of proteins and nucleic acids
por: Ashkenazy, Haim, et al.
Publicado: (2010) -
Synonymous site conservation in the HIV-1 genome
por: Mayrose, Itay, et al.
Publicado: (2013) -
FastML: a web server for probabilistic reconstruction of ancestral sequences
por: Ashkenazy, Haim, et al.
Publicado: (2012) -
Interleukin-6 and Interferon-α Signaling via JAK1–STAT Differentially Regulate Oncolytic versus Cytoprotective Antiviral States
por: Danziger, Oded, et al.
Publicado: (2018)