Multiple whole genome alignments and novel biomedical applications at the VISTA portal

The VISTA portal for comparative genomics is designed to give biomedical scientists a unified set of tools to lead them from the raw DNA sequences through the alignment and annotation to the visualization of the results. The VISTA portal also hosts the alignments of a number of genomes computed by o...

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Detalles Bibliográficos
Autores principales: Brudno, Michael, Poliakov, Alexander, Minovitsky, Simon, Ratnere, Igor, Dubchak, Inna
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2007
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1933192/
https://www.ncbi.nlm.nih.gov/pubmed/17488840
http://dx.doi.org/10.1093/nar/gkm279
Descripción
Sumario:The VISTA portal for comparative genomics is designed to give biomedical scientists a unified set of tools to lead them from the raw DNA sequences through the alignment and annotation to the visualization of the results. The VISTA portal also hosts the alignments of a number of genomes computed by our group, allowing users to study the regions of their interest without having to manually download the individual sequences. Here we describe various algorithmic and functional improvements implemented in the VISTA portal over the last 2 years. The VISTA Portal is accessible at http://genome.lbl.gov/vista.

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