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Mutations in the 3'-untranslated region of GATA4 as molecular hotspots for congenital heart disease (CHD)
BACKGROUND: The 3'-untranslated region (3'-UTR) of mRNA contains regulatory elements that are essential for the appropriate expression of many genes. These regulatory elements are involved in the control of nuclear transport, polyadenylation status, subcellular targetting as well as rates...
Autores principales: | Reamon-Buettner, Stella Marie, Cho, Si-Hyen, Borlak, Juergen |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1933416/ https://www.ncbi.nlm.nih.gov/pubmed/17592645 http://dx.doi.org/10.1186/1471-2350-8-38 |
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