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Antisense oligonucleotide induced exon skipping and the dystrophin gene transcript: cocktails and chemistries

BACKGROUND: Antisense oligonucleotides (AOs) can interfere with exon recognition and intron removal during pre-mRNA processing, and induce excision of a targeted exon from the mature gene transcript. AOs have been used in vitro and in vivo to redirect dystrophin pre-mRNA processing in human and anim...

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Detalles Bibliográficos
Autores principales:	Adams, Abbie M, Harding, Penny L, Iversen, Patrick L, Coleman, Catherine, Fletcher, Sue, Wilton, Steve D
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2007
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1933433/ https://www.ncbi.nlm.nih.gov/pubmed/17601349 http://dx.doi.org/10.1186/1471-2199-8-57

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