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Divergent Evolution of Human p53 Binding Sites: Cell Cycle Versus Apoptosis

The p53 tumor suppressor is a sequence-specific pleiotropic transcription factor that coordinates cellular responses to DNA damage and stress, initiating cell-cycle arrest or triggering apoptosis. Although the human p53 binding site sequence (or response element [RE]) is well characterized, some gen...

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Detalles Bibliográficos
Autores principales:	Horvath, Monica M, Wang, Xuting, Resnick, Michael A, Bell, Douglas A
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2007
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1934401/ https://www.ncbi.nlm.nih.gov/pubmed/17677004 http://dx.doi.org/10.1371/journal.pgen.0030127

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