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Divergent Evolution of Human p53 Binding Sites: Cell Cycle Versus Apoptosis

The p53 tumor suppressor is a sequence-specific pleiotropic transcription factor that coordinates cellular responses to DNA damage and stress, initiating cell-cycle arrest or triggering apoptosis. Although the human p53 binding site sequence (or response element [RE]) is well characterized, some gen...

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Detalles Bibliográficos
Autores principales: Horvath, Monica M, Wang, Xuting, Resnick, Michael A, Bell, Douglas A
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1934401/
https://www.ncbi.nlm.nih.gov/pubmed/17677004
http://dx.doi.org/10.1371/journal.pgen.0030127

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