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DNA bar coding and pyrosequencing to identify rare HIV drug resistance mutations
Treatment of HIV-infected individuals with antiretroviral agents selects for drug-resistant mutants, resulting in frequent treatment failures. Although the major antiretroviral resistance mutations are routinely characterized by DNA sequencing, treatment failures are still common, probably in part b...
Autores principales: | Hoffmann, Christian, Minkah, Nana, Leipzig, Jeremy, Wang, Gary, Arens, Max Q., Tebas, Pablo, Bushman, Frederic D. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1934997/ https://www.ncbi.nlm.nih.gov/pubmed/17576693 http://dx.doi.org/10.1093/nar/gkm435 |
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