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RNA structure is a key regulatory element in pathological ATM and CFTR pseudoexon inclusion events

Genomic variations deep in the intronic regions of pre-mRNA molecules are increasingly reported to affect splicing events. However, there is no general explanation why apparently similar variations may have either no effect on splicing or cause significant splicing alterations. In this work we have...

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Detalles Bibliográficos
Autores principales: Buratti, Emanuele, Dhir, Ashish, Lewandowska, Marzena A., Baralle, Francisco E.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2007
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1935003/
https://www.ncbi.nlm.nih.gov/pubmed/17580311
http://dx.doi.org/10.1093/nar/gkm447