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The novel PIAS-like protein hZimp10 is a transcriptional co-activator of the p53 tumor suppressor

The tumor suppressor, p53, plays critical roles in the cell cycle progression, DNA repair and apoptosis. The PIAS proteins (protein inhibitor of activated STAT) were originally identified as inhibitors of the JAK-STAT pathway. Subsequently, crosstalk between the PIAS proteins and other signaling pat...

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Detalles Bibliográficos
Autores principales: Lee, Jane, Beliakoff, Jason, Sun, Zijie
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1935018/
https://www.ncbi.nlm.nih.gov/pubmed/17584785
http://dx.doi.org/10.1093/nar/gkm476