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Engineered apoptotic nucleases for chromatin research

We have created new genomics tools for chromatin research by genetically engineering the human and mouse major apoptotic nucleases that are responsible for internucleosomal DNA cleavage, DNA fragmentation factor (DFF). Normally, in its inactive form, DFF is a heterodimer composed of a 45-kDa chapero...

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Detalles Bibliográficos
Autores principales: Xiao, Fei, Widlak, Piotr, Garrard, William T.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1935020/
https://www.ncbi.nlm.nih.gov/pubmed/17626049
http://dx.doi.org/10.1093/nar/gkm486