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Natalizumab: A new treatment for relapsing remitting multiple sclerosis

Natalizumab, a new disease-modifying therapy for relapsing remitting multiple sclerosis (RRMS), is a humanized monoclonal antibody which binds to α(4)β(1)-integrin. In a Phase 3 trial, 2 years of natalizumab monotherapy reduced the mean annualized relapse rate (ARR) by 68% compared with placebo (p &...

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Detalles Bibliográficos
Autor principal:	Hutchinson, Michael
Formato:	Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2007
Materias:	Reviews
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1936307/ https://www.ncbi.nlm.nih.gov/pubmed/18360634

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