Cargando…
Loss-of-function genetic diseases and the concept of pharmaceutical targets
The biomedical world relies heavily on the definition of pharmaceutical targets as an essential step in the drug design process. It is therefore tempting to apply this model to genetic diseases as well. However, whereas the model applies well to gain-of-function genetic diseases, it is less suited t...
| Autor principal: | |
|---|---|
| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2007
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1936415/ https://www.ncbi.nlm.nih.gov/pubmed/17674486 http://dx.doi.org/10.1186/1750-1172-2-30 |