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Of mice and men: phylogenetic footprinting aids the discovery of regulatory elements

Phylogenetic footprinting is an approach to finding functionally important sequences in the genome that relies on detecting their high degrees of conservation across different species. A new study shows how much it improves the prediction of gene-regulatory elements in the human genome.

Detalles Bibliográficos
Autores principales: Zhang, Zhaolei, Gerstein, Mark
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2003
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC193683/
https://www.ncbi.nlm.nih.gov/pubmed/12814519
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author Zhang, Zhaolei
Gerstein, Mark
author_facet Zhang, Zhaolei
Gerstein, Mark
author_sort Zhang, Zhaolei
collection PubMed
description Phylogenetic footprinting is an approach to finding functionally important sequences in the genome that relies on detecting their high degrees of conservation across different species. A new study shows how much it improves the prediction of gene-regulatory elements in the human genome.
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spelling pubmed-1936832003-09-15 Of mice and men: phylogenetic footprinting aids the discovery of regulatory elements Zhang, Zhaolei Gerstein, Mark J Biol Minireview Phylogenetic footprinting is an approach to finding functionally important sequences in the genome that relies on detecting their high degrees of conservation across different species. A new study shows how much it improves the prediction of gene-regulatory elements in the human genome. BioMed Central 2003 2003-06-06 /pmc/articles/PMC193683/ /pubmed/12814519 Text en Copyright © 2003 BioMed Central Ltd
spellingShingle Minireview
Zhang, Zhaolei
Gerstein, Mark
Of mice and men: phylogenetic footprinting aids the discovery of regulatory elements
title Of mice and men: phylogenetic footprinting aids the discovery of regulatory elements
title_full Of mice and men: phylogenetic footprinting aids the discovery of regulatory elements
title_fullStr Of mice and men: phylogenetic footprinting aids the discovery of regulatory elements
title_full_unstemmed Of mice and men: phylogenetic footprinting aids the discovery of regulatory elements
title_short Of mice and men: phylogenetic footprinting aids the discovery of regulatory elements
title_sort of mice and men: phylogenetic footprinting aids the discovery of regulatory elements
topic Minireview
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC193683/
https://www.ncbi.nlm.nih.gov/pubmed/12814519
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