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Tracking evolution's footprints in the genome
The strategy of using 'phylogenetic footprinting' to find regulatory sites that are conserved between pairs of related complex genomes has led to the development of a suite of computational tools that succeed in finding functionally important transcription-factor-binding sequences.
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2003
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC193687/ https://www.ncbi.nlm.nih.gov/pubmed/12818003 http://dx.doi.org/10.1186/1475-4924-2-9 |
Sumario: | The strategy of using 'phylogenetic footprinting' to find regulatory sites that are conserved between pairs of related complex genomes has led to the development of a suite of computational tools that succeed in finding functionally important transcription-factor-binding sequences. |
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