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Tracking evolution's footprints in the genome

The strategy of using 'phylogenetic footprinting' to find regulatory sites that are conserved between pairs of related complex genomes has led to the development of a suite of computational tools that succeed in finding functionally important transcription-factor-binding sequences.

Detalles Bibliográficos
Autor principal: Weitzman, Jonathan B
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2003
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC193687/
https://www.ncbi.nlm.nih.gov/pubmed/12818003
http://dx.doi.org/10.1186/1475-4924-2-9
Descripción
Sumario:The strategy of using 'phylogenetic footprinting' to find regulatory sites that are conserved between pairs of related complex genomes has led to the development of a suite of computational tools that succeed in finding functionally important transcription-factor-binding sequences.