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Image-Based Modeling Reveals Dynamic Redistribution of DNA Damage into Nuclear Sub-Domains

Several proteins involved in the response to DNA double strand breaks (DSB) form microscopically visible nuclear domains, or foci, after exposure to ionizing radiation. Radiation-induced foci (RIF) are believed to be located where DNA damage occurs. To test this assumption, we analyzed the spatial d...

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Detalles Bibliográficos
Autores principales:	Costes, Sylvain V, Ponomarev, Artem, Chen, James L, Nguyen, David, Cucinotta, Francis A, Barcellos-Hoff, Mary Helen
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2007
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1937017/ https://www.ncbi.nlm.nih.gov/pubmed/17676951 http://dx.doi.org/10.1371/journal.pcbi.0030155

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