Prevalence, clinical relevance and characterization of circulating cytotoxic CD4(+)CD28(- )T cells in ankylosing spondylitis

Circulating CD3(+)CD4(+)CD28(- )cells exhibit reduced apoptosis and were found to be more enriched in patients with ankylosing spondylitis than in age-matched healthy control individuals (7.40 ± 6.6% versus 1.03 ± 1.0%; P < 0.001). Levels of CD4(+)CD28(- )T cells correlate with disease status as...

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Detalles Bibliográficos
Autores principales: Duftner, Christina, Goldberger, Christian, Falkenbach, Albrecht, Würzner, Reinhard, Falkensammer, Barbara, Pfeiffer, Karl P, Maerker-Hermann, Elisabeth, Schirmer, Michael
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2003
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC193730/
https://www.ncbi.nlm.nih.gov/pubmed/12932293

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