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A comparative study of the inhibitory effects of interleukin-1 receptor antagonist following administration as a recombinant protein or by gene transfer

Anakinra, the recombinant form of IL-1 receptor antagonist (IL-1Ra), has been approved for clinical use in the treatment of rheumatoid arthritis as the drug Kineret™, but it must be administered daily by subcutaneous injection. Gene transfer may offer a more effective means of delivery. In this stud...

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Detalles Bibliográficos
Autores principales:	Gouze, Jean-Noel, Gouze, Elvire, Palmer, Glyn D, Liew, Victor S, Pascher, Arnulf, Betz, Oliver B, Thornhill, Thomas S, Evans, Christopher H, Grodzinsky, Alan J, Ghivizzani, Steven C
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2003
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC193732/ https://www.ncbi.nlm.nih.gov/pubmed/12932294

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